Why is it important to try to control seizure activity with one drug therapy if possible?

• A. Increases adherence
• B. Increases toxicity
• C. Increases cost
• D. Reduces efficacy

Answer: (A)

The main idea is that simpler treatment improves adherence. When seizure control can be achieved with one medication, the regimen is easier for the patient to follow—fewer doses, fewer pills to take, and less potential for scheduling errors. This easier plan makes it more likely the patient will take the medicine consistently, which is essential for keeping seizures under control. Additionally, using a single drug means fewer drug–drug interactions and often fewer side effects, both of which support better adherence and safety. While adding a second drug can be necessary in some cases, it tends to increase toxicity risk, cost, and regimen complexity, which can undermine adherence.