Which statement correctly reflects benzodiazepine dependence management?

• A. Do not stop abruptly after prolonged use.
• B. Stop abruptly to reduce dependence.
• C. Continue taking even if not effective.
• D. Double the dose if sleep is not achieved.

Answer: (A)

Managing benzodiazepine dependence focuses on a gradual taper after long-term use. Abrupt cessation following prolonged use can trigger a withdrawal syndrome with insomnia, anxiety, irritability, tremors, autonomic symptoms, and even seizures, making sudden stopping dangerous. Therefore, the best approach is to slowly reduce the dose under medical supervision to allow the body to adjust and minimize withdrawal. Keeping the medication just because it sometimes helps sleep or mood doesn’t resolve dependence; continuing the drug maintains reliance and exposure to adverse effects. Increasing the dose for sleep worsens dependence and tolerance and raises the risk of overdose, especially with alcohol or other depressants.