Which medication listed for the patient is most likely to interact negatively with phenytoin?

Prepare for the EDAPT Intracranial Regulation Test with interactive flashcards and multiple choice questions. Each question is accompanied by helpful hints and explanations to boost your readiness. Get started today and ensure your success!

Multiple Choice

Which medication listed for the patient is most likely to interact negatively with phenytoin?

Explanation:
Phenytoin is a strong inducer of liver enzymes, which speeds up the breakdown of many drugs. Warfarin’s effect depends on maintaining a certain level in the blood, so when phenytoin ramps up metabolism, warfarin is cleared more quickly and its anticoagulant effect drops. That can lead to a subtherapeutic anticoagulation level and a higher risk of clotting events. The other medications listed don’t have as robust or reliable a negative interaction with phenytoin, so the interaction that most concerns practice is with Warfarin.

Phenytoin is a strong inducer of liver enzymes, which speeds up the breakdown of many drugs. Warfarin’s effect depends on maintaining a certain level in the blood, so when phenytoin ramps up metabolism, warfarin is cleared more quickly and its anticoagulant effect drops. That can lead to a subtherapeutic anticoagulation level and a higher risk of clotting events. The other medications listed don’t have as robust or reliable a negative interaction with phenytoin, so the interaction that most concerns practice is with Warfarin.

More Multiple Choice Questions
Subscribe

Get the latest from Passetra

You can unsubscribe at any time. Read our privacy policy