Valproic acid is most commonly prescribed for which condition in patients without a history of seizures?

• A. Bipolar disorder
• B. Anxiety disorder
• C. Migraine
• D. Generalized seizures

Answer: (A)

Valproic acid acts as a mood stabilizer and is especially effective for managing mania in bipolar disorder. In patients who do not have epilepsy, its most common non-seizure use is to treat bipolar disorder, including acute mania and maintenance of mood stability. While it can be used for migraine prevention, that indication is less common than its role in bipolar disorder. Generalized seizures would involve a seizure history, which the question excludes, and anxiety disorders are not typical primary targets for valproate. So bipolar disorder is the best fit for a patient without a history of seizures.